GD真人

澳科大再次榮獲教育部自然科學獎一等獎

guojiajiaoyubuwangzhanriqianzhengshigongbule2018niandugaodengxuexiaokexueyanjiuyouxiuchengguojiang(kexuejishu)huojiangmingdan,qizhongaomenkejidaxueyidiyiwanchengdanweironghuozirankexuejiangyidengjiang,weigangaodiqugainianduweiyihuodecishurongdegaoxiao,zheyeshiaokedaji2014nianhoudierciyidiyiwanchengdanweihuodecirongyu。

aokedaxiaochangjianzhongyaozhiliangyanjiuguojiazhongdianshiyanshizhurenliuliangjiangzuojiaoshou

aokedacicihuojiangdexiangmuwei「yizhixibaozengzhiyufenhuayichangdexinjizhiyanjiu」,hezuowanchengdanweihuanbaokuoguangzhouzhongyiyaodaxuehefudandaxue。diyiwanchengrenweiaokedaxiaochangjianzhongyaozhiliangyanjiuguojiazhongdianshiyanshizhurenliuliangjiangzuojiaoshou,qitawanchengrenbaokuofudandaxueyaoxueyuanshenxiaoyanjiaoshou、guangzhouzhongyiyaodaxueguojizhongyiyaozhuanhuayixueyanjiusuoliuzhongqiusuochang、aokedazhongyiyaoxueyuanzhouhuafuyuanchang、zhongyaozhiliangyanjiuguojiazhongdianshiyanshilianglixianzhulizhuren、fanxingxingzhulijiaoshou、luopeifujiaoshou、litingfujiaoshou、yaoxueyuanxieyingfujiaoshou、zhongyaozhiliangyanjiuguojiazhongdianshiyanshixiaowenluanjiaoshou、yaoxiaojunjiaoshou、huangjinweifujiaoshou、fuxiaochangjianzhongyaozhiliangyanjiuguojiazhongdianshiyanshifuzhurenjiangzhihongjiangzuojiaoshou、yaoxueyuanzhuyizhunyuanchangjiguangzhouzhongyiyaodaxuelulinlinjiaoshou。cihuojiangxiangmuzhuyaoweiraoxibaozengzhiyufenhuayichangzheyileifengshiguanjieyanheaizhenglinchuangchangjiannanzhijibingdegongtongbinglihuanjie,jichengheyingyongduoxuekedexianjinjishuyufangfa,jiehezhongyiyaolinchuangjingyan,jinxingyixiliedechuangxinxingyanjiu,qudeleduoxiangtupoxingdeyanjiuchengguo。

前排左起: 梁麗嫻助理主任、周華副院長、校長劉良講座教授、蕭文鸞教授、羅培副教授、李婷副教授;
GD真人後排左起: 謝瑩副教授、黃錦偉副教授

aomenkejidaxuezichuangxiaoyilaizhilifazhangaoshuipingdekexueyanjiu,zhuzhongkeyanyuaomentesejiehe,dazaoyoushiyanjiulingyu,xianhouchenglilezhongyaozhiliangyanjiuguojiazhongdianshiyanshijiyueqiuyuxingxingkexueguojiazhongdianshiyanshi;peiheaomentequzhengfu「jiaoyuxingao、rencaijianao」deshizhengfangzhen,weiaomenpeiyuaiguoaiaoyouxiuchuangxinrencai,bingweiaomenjingjishiduduoyuanfazhan、shehuijinbuzuochugongxian。zuijin,aokedahuopikaibanneiwaiquankeyixuexueshixueweikecheng,xianzhengjinxingzhaoshengbingjiangzujianchengliyixueyuan,jiehexianyoudezhongyiyaoxueyuan、yaoxueyuan、jiankangkexuexueyuanjizhongyaozhiliangyanjiuguojiazhongdianshiyanshideng,fahuixietongliliang,jinxingkuaxuekedejiaochayanjiu,cujinyixuelingyudekeyan,weirenleifuzhizuochugongxian。

GD真人「yizhixibaozengzhiyufenhuayichangdexinjizhiyanjiu」qudelejutupoxingyiyideyanjiuchengguo,budanhuoguojiabanfazirankexuejiangyidengjiang,genghuodeguojixueshujiedegaodukendinghepingjia。ciyanjiushoucijieshilefenxuanlianjiedanbai10(snx10)jiyinhenf-κbxinhaotongluzaileifengshiguanjieyanguqinshibinglizhongdeguanjianzuoyong,weijiejuegaileijibinghuanzhegupohuandeshijienantikaipilexintujing。

aokedazhongyaozhiliangyanjiuguojiazhongdianshiyanshijuyouxianjinyiqijixitongjinxingkeyanshiyan

ciyanjiudelingyixiangtupojiushishoucifaxiankangguanjieyanzhongyaohuoxingchengfenhuangtongleihuahewuzaichangdaoneicunzaizhudaixiediaokongxinjizhi——「changjubuxunhuan」,shiyaowuzaichangdaoneiyinjubuxunhuaneryanchangzhiliushijian,zengqiangliaoxiao,bingjucishouchuangle「ganchangdisanxunhuan」deyaowudaixieyanjiuxinmoshi,gaimoshimibuleyuanyouganchangxunhuanhechangchangxunhuandebuzu。tongshi,yizaicijichushangshoucitichuleyaowutineidaixie「xuanzhuanmenlilun」,bingyicichanshilekangguanjieyanzhongyaohuoxingchengfenzaitineidaixiediaokongxinjizhi。gaililunyouzhuwujiejuezhongyaozhiliaoaizhenghezishenmianyixingjibingshihuangtongleiyaoxiaochengfennanxishoudenanti,huoguojizhumingxuezhemixiegendaxuestephensonjiaoshoudengduigaililungeiyulegaodupingjia。

此研究項目還首次發現了中藥血根碱通過作用於「氧化酶3-氧自由基-蛋氨酸還原酶A」軸而誘導表皮生長因子受體(EGFR)蛋白降解或抑制細胞代謝而抗細胞增殖與分化異常的新機制,這為解決小細胞肺癌靶標藥物治療耐藥性的世界難題開啟了新方向。此研究成果在國際著名的抗氧化研究期刊Antioxidants & Redox SignalingGD真人以封面論文發表。該種藥物作用新機制已被中國、日本和韓國等多位著名學者所證實和認同。

GD真人jiaoyubukejijiangjingjiaoyubujianglipingshenweiyuanhuipingshen、jiangliweiyuanhuishendinghejiaoyubupizhun,benniandugongyou318xiang/renhuojiang,fenzirankexuejiang、jishufamingjiang、kejijinbujiangjiqingniankexuejiangsigedalei,shijinciwuguojiasandajiangdejiaoyubukejijiangxiang。zirankexuejiangzhuyaojianglizaijichuyanjiuheyingyongjichuyanjiuzhongzuochuzhongyaokexuefaxiandegerenhedanwei。gangaodiquyouwusuogaoxiaodexiangmuhuojiang,qizhongaomenkejidaxuede「yizhixibaozengzhiyufenhuayichangdexinjizhiyanjiu」xiangmuhuodezirankexuejiangyidengjiang,xianggangkejidaxue、xianggangligongdaxue、xianggangjinhuidaxuefenbiehuodeyixiangzirankexuejiangerdengjiang,xianggangzhongwendaxuehuodeyixiangjishufamingjiangerdengjiang。

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